There are many strains with the word "Madness" in their name, but two varieties exist on the cannabis market with the word itself.

World of Seeds created their Madness cultivar by combining a Brazil landrace sativa with a combination of Cinderella 99 x Matanuska Tundra. The top reported aromas of the Madness strain are fruit, pepper, and herbs. It is said to taste like tropical fruit, herbs, and spices.

Madness from Hazeman seeds is a combination of Bubba Kush and G-13. It is said to smell like earth, diesel, and spices. Its top reported aromas are herbs, fuel, and wet soil.